Impact of transcranial direct current stimulation on cognitive function, brain functional segregation, and integration in patients with mild cognitive impairment according to amyloid-beta deposition and APOE ε4-allele
D. W. Kang, S.-M. Wang, T. Y. Kim, D. H. Kim, H.-R. Na, N.-Y. Kim, C. U. Lee, H. K. Lim
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AbstractAnodal transcranial direct current stimulation (anodal-tDCS) is known to improve cognition (Liu, C.S., et al., 2017) and normalize abnormal network configuration during resting-state functional magnetic resonance imaging (fMRI) in patients with mild cognitive impairment (MCI) (Binnewijzend, M.A., et al., 2012). We aimed to evaluate the impact of sequential anodal-tDCS on cognitive functions, functional segregation, and integration parameters in patients with MCI, according to high-risk factors for Alzheimer’s disease (AD): amyloid-beta (Aβ) deposition and APOE ε4-allele status.Keywords: amyloid beta deposition; APOE ε4-allele; mild cognitive impairment; transcranial direct current stimulation
D. W. Kang, S.-M. Wang, T. Y. Kim, D. H. Kim, H.-R. Na, N.-Y. Kim, C. U. Lee, H. K. Lim (2022). Impact of transcranial direct current stimulation on cognitive function, brain functional segregation, and integration in patients with mild cognitive impairment according to amyloid-beta deposition and APOE ε4-allele. Gerontechnology, 21(s),2-2
https://doi.org/10.4017/gt.2022.21.s.822.2.sp3